Experimental Isovalthinuria. Iii. Induction by Bile Acids, and Hypocholesterolemic Agents.
نویسنده
چکیده
Some bile acids (dehydrocholic, cholic, chenodeoxycholic, ursodeoxycholic, and deoxycholic acids), and some hypocholesterolemic agents (22, 25 diazacholestanol, 20,25-diazacholesterol, triparanol, and SKF 525-A) are the inducers of isovalthinuria in guinea pig. Administration of methionine appears to increase the pool of sulfur compound which participates in the formation of isovalthine. Cholesterol appears to have no enhancing effect on the induction activity of isovalthinuria inducers. The mechanism of isovalthine formation and the role of sulfur amino acids in lowering blood cholesterol are discussed. ∗PMID: 14168971 [PubMed indexed for MEDLINE] Copyright c ©OKAYAMA UNIVERSITY MEDICAL SCHOOL Acta Med. Okayama 17, 273-278 (1963) EXPERIMENTAL ISOVALTHINURIA* Ill. INDUCTION BY BILE ACIDS, AND HYPOCHOLESTEROLEMIC AGENTS
منابع مشابه
Experimental Isovalthinuria. Iv. Incorporation of S35-methionine or S35-cystine into Urinary Isovalthine.
In the course of experimental isovalthinuria induced by cholic acid, S35-methionine or S35cystine administered was incorporated into urinary isovalthine in guinea pigs. Sulfur atom of cysteine seems to be utilized much better for isovalthine synthesis than that of methionine. ∗PMID: 14204460 [PubMed indexed for MEDLINE] Copyright c ©OKAYAMA UNIVERSITY MEDICAL SCHOOL Acta Med. Okayama 18, 65-70 ...
متن کاملHypocholesterolemic Effects of Nutraceuticals Produced from the Red Microalga Porphyridium sp in Rats
Red microalgae contain functional sulfated polysaccharides (containing dietary fibers), polyunsaturated fatty acids, zeaxanthin, vitamins, minerals, and proteins. Studies in rat models support the therapeutic properties of algal biomass and isolated polysaccharides. Algal products incorporated into rat diets were found to significantly improve total serum cholesterol, serum triglycerides, hepat...
متن کاملHypocholesterolemic effects of Lactobacillus plantarum KCTC3928 by increased bile acid excretion in C57BL/6 mice.
OBJECTIVE We doubly coated Lactobacillus plantarum KCTC3928 with proteins and polysaccharide compounds to enhance its acid and bile resistance. The present study investigated the hypocholesterolemic effects of double-coated L. plantarum KCTC3928 in C57BL/6 mice fed a high-fat diet. The effects of live and dead bacteria were compared. METHODS Six-week-old C57BL/6 male mice were divided into th...
متن کاملComparison of the mechanisms proposed to explain the hypocholesterolemic effect of soybean protein versus casein in experimental animals.
Diets containing soybean protein generally induce low levels of serum cholesterol in experimental animals, when compared with diets containing casein. The hypocholesterolemia in animals fed soybean protein is associated with increased rates of fecal excretion of bile acids and neutral steroids, low liver cholesterol concentrations, increased numbers of hepatic apo B/E receptors, increased rates...
متن کاملIdentification of a Novel Hypocholesterolemic Protein, Major Royal Jelly Protein 1, Derived from Royal Jelly
Royal jelly (RJ) intake lowers serum cholesterol levels in animals and humans, but the active component in RJ that lowers serum cholesterol level and its molecular mechanism are unclear. In this study, we set out to identify the bile acid-binding protein contained in RJ, because dietary bile acid-binding proteins including soybean protein and its peptide are effective in ameliorating hyperchole...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Acta medicinae Okayama
دوره 17 شماره
صفحات -
تاریخ انتشار 1963